Emixustat hydrochloride ( ACU-4429 hydrochloride )

产品货号. M10504 CAS No. 1141934-97-5

Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM.

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
2MG	￥794	有现货
5MG	￥1450	有现货
10MG	￥2309	有现货
25MG	￥3872	有现货
50MG	￥5565	有现货
100MG	￥8084	有现货
200MG	获取报价	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

拼团产品询价大包装询价加入购物车

生物学信息

产品名称

Emixustat hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM.
产品描述

Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM; reduces the production of visual chromophore (11-cis retinal) in wild-type mice following a single oral dose (ED50 = 0.18 mg/kg).Other Indication Phase 3 Clinical
同义词

ACU-4429 hydrochloride
通路

Others
靶点

Other Targets
受体

Other Targets
研究领域

Other Indications
适应症

Other Disease

化学信息

CAS Number

1141934-97-5
分子量

299.84
分子式

C16H26ClNO2
纯度

>98% (HPLC)
溶解度

DMSO: ≥ 44 mg/mL
SMILES

C1CCC(CC1)COC2=CC=CC(=C2)C(CCN)O.Cl
化学全称

Benzenemethanol, α-(2-aminoethyl)-3-(cyclohexylmethoxy)-, hydrochloride (1:1), (αR)-

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Kiser PD, et al. Nat Chem Biol. 2015 Jun;11(6):409-15.
2. Bavik C, et al. PLoS One. 2015 May 13;10(5):e0124940.
3. Zhang J, et al. J Clin Invest. 2015 Jul 1;125(7):2781-94.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册

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